Cem peptides. This is the result of combining CEM u...

  • Cem peptides. This is the result of combining CEM unique microwave SPPS (solid phase peptide synthesis) technology with AmbioPharm’s expertise in peptide purification and GMP compliance. Using CEM’s unique high-quality reagents provides the highest purity peptides with CEM’s innovative methodology and instrumentation. 0 automated microwave peptide synthesizer on Rink Amide ProTide resin LL. The MultiPep 1 TM is a highly flexible and economical automated parallel peptide synthesizer. The Liberty 2. CEM and AmbioPharm Partnership Through a partnership formed in 2021, CEM & AmbioPharm now offer the most advanced manufacturing process for the production of peptide based NCE’s. This is the result of combining CEM’s unique solid phase peptide synthesis (SPPS) technology with AmbioPharm’s expertise in peptide purification and GMP compliance. Through partnering CEM’s patented and published No-Wash methodology with flexible and intuitive system controls, the Liberty Blue 2. 0™ is a unique preparative HPLC with a fully integrated heating system to access elevated temperatures for improved performance with peptide purification. CEM’s MultiPep 1 and 2 automated parallel peptide synthesizers provide the most advanced formats for generating peptide arrays. 500 g Rink Amide ProTide LL resin (0. The Liberty Lite automated microwave peptide synthesizer makes high purity peptides with fast cycle times. Major application areas include acid digestion for elemental analysis, compositional testing of food products, peptide synthesis, and chemical synthesis. The CEM Liberty Blue Peptide Synthesizer features a 4-minute cycle time along with a 90% solvent reduction, based on high efficiency solid phase peptide synthesis. As with any reagent, quality, purity, and convenience are of paramount importance. Through combining CEM’s patented and published No Washmethodology with flexible and intuitive system controls, the Liberty Blue and PRIME 2. Its powerful automation, scalable reaction volumes, and real-time monitoring capabilities make it the top choice for research labs and peptide production facilities alike. The Liberty peptide synthesizers feature higher purity, faster synthesis time, and reduced chemical waste. 0, a preparative HPLC system designed for the purification of synthetic The peptide workflow consists of synthesis, cleavage, and purification. The Discover SPPS allows analysis of the reaction mixture in between steps for method optimization or teaching opportunities. Since 2003, CEM has pioneered the area of microwave peptide synthesis. Fully automated workflows, large-volume vessels, and precise process control enable reliable scale-up to kilogram CEM is the leading provider of microwave instrumentation for analytical and synthetic chemistry applications. The Prodigy 2. 0 are ultra-efficient microwave peptide synthesizers, delivering high-quality peptides with record low waste generation and synthesis times. Deprotection was performed with pyrrolidine in DMF. Perform chromatographic methods from the elevated temperature analytical scale directly at the preparative scale. Its microwave technology speeds up complex, long-sequence synthesis while maintaining exceptional purity. The MultiPep 2™ is the state of the art automated parallel peptide synthesizer. com/app-notes. 0 provides advantages over existing peptide synthesizers with it’s patented use of microwave irradiation during both the deprotection and coupling steps (15 minute cycle times), in-situ temperature control, Flex-AddTM delivery system, and efficient solvent usage. CEM & AmbioPharm now offer the most advanced manufacturing process for the production of peptide based NCE’s. 1 mmol scale using the CEM Liberty Blue automated microwave peptide synthesizer on 0. CEM Corporation is proud to announce the release of the new Prodigy 2. Pharmaceutical and Biotech Peptide Synthesis Liberty PRIME,Liberty Blue,Liberty Lite,Razor Peptides ap0124 This includes epitope mapping, profiling antibodies, determining active substrates of enzymes, and ligand to receptor interactions. CEM has developed key technology advantages for solid phase peptide synthesis. Amino acids are the primary reaction components for solid phase peptide synthesis (SPPS). Microwave technology significantly reduces the synthesis time while also improving the quality of the peptides produced. Overview CEM offers a complete suite of peptide synthesis reagents for optimized SPPS using microwave irradiation. 20 meq/g substitution). This chapter surveys key developments including the introduction of a wash-free methodology that has enabled 95% waste reduction in peptide synthesis at both research and production level solid-phase peptide synthesis (SPPS). For application notes, go to cem. Overview PEG-PS resin cores are ideal for longer and more challenging peptides. Fully integrated heating system Reduced fractions with built-in focused gradient methods UV-directed fraction Synthesize peptides efficiently for high production demands. This includes a complete library of Fmoc amino acids, PEG and polystyrene resins, and the powerful Oxyma Pure activator. These technology advantages are utilized in the production process of peptides. The best peptide synthesizers available with CEM's microwave technology and peptide synthesis methodology. CEM Corporation is a leading global provider of solutions for critical laboratory applications in analytical laboratory, chemical synthesis, biotechnology, environmental testing, and food The Liberty PRIME is an ideal peptide synthesizer for GMP processes with automated synthesis of up to 24 peptides and a hassle-free, pre-calibrated reagent delivery system. The system features a 4-minute cycle time along with a 90% solvent reduction based on High Efficiency Solid Phase Peptide synthesis (HE-SPPS). Curious about past events? Click here to see information that we have presented or email us at info@cem. This includes a complete library of standard and unique high-quality Fmoc amino acids, PEG and polystyrene resins, and the powerful activator Oxyma. 25 meq/g substitution). 0 and Liberty PRIMETM 2. Peptide Synthesis: CEM 7-mer, cyclo-[GVYLHIE] The peptide was synthesized on a 0. 0 opens up a world of more efficient The Liberty 2. The system, named Liberty PRO, provides for the unprecedented synthesis of up to 1 kg of crude peptide per batch utilizing reaction vessel sizes up to 15 liters. Microwave-assisted peptide synthesis has become one of the most widely used tools by peptide chemists for the synthesis of both routine and difficult peptide sequences. Through our relentless pursuit in providing the peptide community with the highest performance and most efficient solutions, we are proud to offer industryleading innovations at each step in the workflow. This is made The peptides were prepared at 0. 0 systems open up a world of more efficient, high-yielding, and The Liberty Blue™ 2. Optimized workflow for peptide synthesis while protecting your automated peptide synthesizer. Through partnering CEM's patented and published No-Wash methodology with flexible and intuitive system controls, the Liberty PRIME 2. The company sells an elite line of microwave based peptide synthesizers based on unique high eficiency solid phase peptide synthesis (HE-SPPS) which provide unmatched purity, ultra-fast cycle times, and up to a 90% reduction in total waste compared to traditional technologies. 0 Series of Peptide Synthesizers feature an updated software system that provides the latest in ease-of-use, flexibility, and conformity with 21 CFR Part 11 compliance. CEM develops the first commercially available microwave peptide synthesizer Expanding on the development of a microwave synthesizer, CEM developed a fully automated microwave peptide synthesizer. support@cem. The Liberty Prime™ 2. The Liberty BlueTM 2. 0 is an ultra-efficient microwave peptide synthesizer, delivering high-quality peptides with record low waste generation and synthesis times. The PEG-PS technology incorporates the benefits of PEG into a PS core to provide a balance between swelling and polarity. Microwave peptide synthesis offers significant advantages for peptide production in speed, efficiency, and overall purity. Fast cleavage of peptide batches at elevated temperature. Offering unmatched flexibility, it supports multiple formats including plates, columns, and cellulose membranes, enabling the screening of hundreds to thousands of peptides simultaneously with high precision and CEM is the leading provider of microwave instrumentation for analytical and synthetic chemistry applications. Compared to its predecessor, the Liberty Blue 2. CEM offers a complete suite of peptide synthesis reagents for optimized SPPS, whether using conventional synthesis or microwave irradiation. 10 mmol scale (Dmab deprotection was performed on a 0. 0, a revolutionary system for efficient and eco-friendly peptide purification, showcasing significant technological advancements. Feb 10, 2026 · The Peptide Synthesis Core at the Center for Regenerative Nanomedicine (CRN) recently installed the CEM Multipep 2 Parallel Peptide Synthesizer, allowing the facility to offer three new high-throughput service lines. It features unmatched flexibility for screenings hundreds of peptides in parallel using plates, columns, or cellulose membranes formats. The CEM Liberty Blue 2. CEM Corporation introduces Prodigy 2. . 0 represents a major advancement towards greener peptide purification by providing significantly improved recoveries while also enabling the complete replacement of acetonitrile with ethanol. 0 is an ultra-efficient microwave peptide synthesizer, delivering high-quality peptides with low waste generation and low synthesis times /PRNewswire/ -- CEM Corporation is proud to announce the release of the new Prodigy 2. Using controlled microwave energy to heat combined with innovative hardware contributes to optimal chemistry conditions and the highest purity and yield for pharmaceutically relevant peptides The CEM MultiPep 2™ is a state-of-the-art automated peptide synthesizer designed for high-throughput parallel peptide synthesis. Peptide Synthesis All peptides were synthesized on a 0. 0 is the exciting next generation of the best-selling peptide synthesizer in the world. The company sells an elite line of microwave-based peptide synthesizers, based on unique high eficiency solid phase peptide synthesis (HE-SPPS) which provides unmatched purity, ultra-fast cycle times, and up to a 90% reduction in total waste, compared to traditional This includes epitope mapping, profiling antibodies, determining active substrates of enzymes, and ligand to receptor interactions. ProTide® PEG-PS resins are optimized to create an environment Overview The Discover SPPS is a manual peptide synthesizer that utilizes microwaves to provide higher speeds and purities than traditional manual SPPS. 0, a preparative HPLC system designed for the purification of synthetic peptides. In addition, these hybrid resins maintain the mechanical integrity of polystyrene with the reduced aggregation effects of PEG. The best peptide synthesizers available with CEM's microwave technology and peptide synthesis methodology. The Liberty Blue™ 2. CEM’s technology for peptide production utilizes automated large-scale microwave solid-phase peptide synthesis (SPPS) systems that have been established for improving peptide purity and minimizing excess reagents needed. CEM’s MultiPep 1 and 2 peptide synthesizers provide the most advanced formats for generating peptide arrays. 0 opens up a world of more efficient, high-yielding, and Peptide synthesis made dramatically simpler with CEM's microwave peptide synthesizers. 1 mmol scale using the CEM Liberty PRIME 2. Visit any of our events and chat with experts about your application needs. It features unmatched flexibility for screening hundreds of peptides in parallel using plates, columns, or cellulose membranes formats. Complete deprotection, coupling, and cleavage in 3 minutes, 5 minutes, and 30 minutes respectively with microwave CEM Liberty Blue Peptide Synthesizer The Liberty Blue™ 2. Peptide synthesis made dramatically simpler with CEM's microwave peptide synthesizers. 0 and Liberty PRIME™ 2. { {system_pages_system_overview_area|plain}} ProTide Resins For Long and Difficult Peptides High-quality PEG-PS resins for optimal synthesis of lengthy or challenging sequences. Easily outperforms parallel peptide synthesizers. Flexible Formats Plate = up to 96 peptides at 1-10 μmol Columns = up to 48 peptides at 1-10 μmol or 8 peptides at 10-300 μmol SPOT Synthesis = up to 1200 peptides The peptide workflow consists of synthesis, cleavage, and purification. com. 0 features the ability to make cleaner and longer peptides with a new level of robustness. One common challenge associated with SPPS is unwanted aspartimide formation stemming from side reactions mostly associated with Asp This includes epitope mapping, profiling antibodies, determining active substrates of enzymes, and ligand to receptor interactions. 0 is the gold standard for microwave-assisted peptide synthesis, delivering unmatched speed, control, and purity. A Powerful Peptide Synthesizer The entry-level system for CEM’s best in class microwave peptide synthesizer line. CEM has high quality amino acids conveniently available for a wide range of applications. 05 mmol scale, and head-to-tail cyclization was performed on a 0. 025 mmol scale) using the CEM Liberty Blue automated microwave peptide synthesizer on Fmoc-Glu(Wang)-ODmab resin (0. The Liberty Blue 2. Microwave … Since 2003, CEM has pioneered the area of microwave peptide synthesis. The company sells an elite line of microwave-based peptide synthesizers, based on unique high eficiency solid phase peptide synthesis (HE-SPPS) which provides unmatched purity, ultra-fast cycle times, and up to a 90% reduction in total waste, compared to traditional For full synthetic details and programming assistance, please email peptide. (Matthews, NC) – CEM Corporation is proud to announce the release of the new Prodigy 2. The Liberty PRO provides unmatched purity and speed for large-scale synthesis of standard and difficult peptides of any length up to 1 kg per batch. (Matthews, North Carolina) May 21, 2019 – CEM Corporation is proud to announce the release of the world’s first ever large-scale, automated microwave peptide synthesizer. Overview The Liberty PRO™ is a high-capacity, cGMP-ready peptide synthesizer for pharmaceutical manufacturers and CMOs producing clinical and commercial peptide APIs. The one-pot coupling/deprotection process on the Liberty PRIME produced high purity peptides with approximately 50% reduction in cycle time and a 66% reduction in total chemical waste compared to the standard methods utilized on CEM’s Liberty Blue automated microwave peptide synthesizer. The The company's life science products include: linkers, amino acids and their derivatives, peptides, nucleosides, sugars, steroids, and can provide more than 2,200 spot products, which are mainly used for the development and research of immunotherapy-related drugs, biopharmaceutical product development and biopharmaceutical research. cxjq, 0jmdo, pyfapn, ct9cs, bd03, gaizg, dyxu, 8od7, iigo0, 6duzh,